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CD8 抗体

This anti-CD8 antibody is a 小鼠 单克隆 antibody detecting CD8 in FACS, IF, IHC (fro), IP 和 IHC (p). Suitable for 绵羊, Cow 和 山羊. This Primary Antibody has been cited in 8+ publications.
产品编号 ABIN1449140
发货至: 中国

Quick Overview for CD8 抗体 (ABIN1449140)

抗原

See all CD8 抗体
CD8

适用

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绵羊, Cow, 山羊

宿主

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小鼠

克隆类型

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单克隆

标记

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This CD8 antibody is un-conjugated

应用范围

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Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

CC63
  • 纯化方法

    Affinity Chromatography on Protein G

    亚型

    IgG2a
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    PBS, 0.09 % Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Lynch, Earley, McGee, Doyle: "Effect of abrupt weaning at housing on leukocyte distribution, functional activity of neutrophils, and acute phase protein response of beef calves." in: BMC veterinary research, Vol. 6, pp. 39, (2010) (PubMed).

    Coad, Clifford, Rhodes, Hewinson, Vordermeier, Whelan: "Repeat tuberculin skin testing leads to desensitisation in naturally infected tuberculous cattle which is associated with elevated interleukin-10 and decreased interleukin-1 beta responses." in: Veterinary research, Vol. 41, Issue 2, pp. 14, (2009) (PubMed).

    Sidders, Pirson, Hogarth, Hewinson, Stoker, Vordermeier, Ewer: "Screening of highly expressed mycobacterial genes identifies Rv3615c as a useful differential diagnostic antigen for the Mycobacterium tuberculosis complex." in: Infection and immunity, Vol. 76, Issue 9, pp. 3932-9, (2008) (PubMed).

    Fulton, Portella, Radke: "Dissemination of bovine leukemia virus-infected cells from a newly infected sheep lymph node." in: Journal of virology, Vol. 80, Issue 16, pp. 7873-84, (2006) (PubMed).

    Harris, Werling, Koss, Monaghan, Taylor, Howard: "Expression of caveolin by bovine lymphocytes and antigen-presenting cells." in: Immunology, Vol. 105, Issue 2, pp. 190-5, (2002) (PubMed).

    Twizere, Kerkhofs, Burny, Portetelle, Kettmann, Willems: "Discordance between bovine leukemia virus tax immortalization in vitro and oncogenicity in vivo." in: Journal of virology, Vol. 74, Issue 21, pp. 9895-902, (2000) (PubMed).

    Winkler, Doster, Jones: "Persistence and reactivation of bovine herpesvirus 1 in the tonsils of latently infected calves." in: Journal of virology, Vol. 74, Issue 11, pp. 5337-46, (2000) (PubMed).

    Gross, Callas, Allison: "Identification and distribution of the costimulatory receptor CD28 in the mouse." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 149, Issue 2, pp. 380-8, (1992) (PubMed).

  • 抗原

    CD8

    别名

    CD8

    背景

    The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell to cell interactions within the immune system. The CD8 antigen, acting as a coreceptor, and the T cell receptor on the T lymphocyte recognize antigen displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains.Synonyms: CD8 alpha chain, CD8A, MAL, T-cell surface glycoprotein CD8 alpha chain, T-lymphocyte differentiation antigen T8/Leu-2
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